Leading B2B2C Startups to Watch in December

Startups have long varied in the gaps and challenges they solve and the solutions they propose. However, they can be grouped into three: (1) Business to Business (B2B) startups, (2) Business to Consumer (B2C) startups and (3) Business to Business to Consumer.

B2B2C technology startups, bridging the gap between businesses and consumers, are poised to become pioneers of the digital age. What is driving this change? It’s the realization that this unexplored territory offers a multitude of benefits.

Top B2B2C startups

One of the most compelling aspects of the B2B2C model is its potential for exponential business growth. As these types of startups serve both businesses and consumers, startups can leverage dual source of income, propelling them forward at an accelerated pace. This duality also strengthens resilience, because the startup is less dependent on a single market segment, thereby diversifying risks.

Partnering with established companies builds brand credibility, while their streamlined approach provides unparalleled convenience to customers. B2B2C startups can focus on their core expertise, through business collaborations, and benefit from a faster path to customer acquisition by leveraging existing customer bases.

In the uncharted waters of tech startups, B2B2C models offer a promising avenue to explore untapped markets and address unmet needs, making them the captains of innovation in the digital age. But what do these B2B2C tech startups look like? Here are the most notable ones that are breaking barriers and exploiting the blue ocean:

Coho AI

Coho AI is a transformative force in the SaaS industry, providing a solution that addresses the challenge of data-driven decision making. This startup leverages the untapped potential of cohort analysis to bring clarity and meaning to the vast sea of ​​SaaS data. Their advanced AI platform seamlessly provides unique and highly sought-after access to customer journey metrics and upsell opportunities.

Using Coho AI’s platform, SaaS and B2C companies can optimize user acquisition by identifying promising user cohorts and tailoring their product experience. As users become high-value customers, the platform seamlessly scales into enterprise sales, providing sales teams with a wealth of data for personalized consultative experiences. Coho AI represents the future of data-driven growth in the SaaS industry, providing insight into the potential of PLG and AI-driven insights. Its innovative approach is poised to shape the future of data-driven growth as technology evolves and data becomes even more abundant. transforms healthcare with its asynchronous telehealth solution. This innovation delivers remarkable efficiency to patients and providers, significantly improving patient satisfaction and streamlining healthcare delivery. By treating low-serious conditions virtually, reduces administrative burdens on providers, allowing them to focus on quality care.

They reduced patient interview times to 13 minutes, reducing emergency room and urgent care visits by 35% and ultimately reducing the cost of care for common conditions. In a healthcare landscape where consumers seek convenience, is a game-changer, providing accessible, consumer-centric care and redefining the patient-provider experience. This company’s leadership is evident in its comprehensive patient interviews, clinical support, and user-friendly digital navigation. is leading the way in the future of asynchronous telehealth.


dv01 leads the charge in structured finance, bridging the gap between lenders and capital markets. Their global platform provides standardized loan-level data and integrated analytics tools, eliminating inefficiencies in existing systems. These outdated technologies have obscured true loan performance, hindered trust, and hampered strategic opportunities. As a one-stop shop, dv01 standardizes raw data and transforms it into actionable insights, enabling clients across financial sectors to make smarter, data-driven decisions.

By focusing on data integrity, they provide transparency across asset classes and data set types, promoting trust and efficiency in the market. With over 400 leading companies under its belt, dv01 is at the forefront of reshaping structured finance with modern technology and data solutions.


Mahmee is at the forefront of maternal support, offering comprehensive pregnancy and postpartum care at a fixed monthly price. With a dedicated team of healthcare professionals, including nurses, doulas, lactation consultants, mental health coaches, nutritionists and care coordinators, Mahmee provides all-inclusive care to meet clients’ unique needs 24 hours a day /24 and 7 days a week.

Their flexible options include virtual and in-person visits, private messages, classes and data-driven care, ensuring clients’ peace of mind during this important journey. Mahmee’s innovative approach simplifies maternity care, unifying a team of experts who support clients every step of the way. It provides proactive and timely care, improving clients’ maternity experience and making it more convenient, cost-effective and reassuring. And through memberships, customers can save over $1,000 per month compared to purchasing these services individually, making Mahmee a game-changer in maternal care and empowering every parent throughout their journey .

Scipher Medicine

Scipher Medicine is trying to combat the $552 billion wasted each year on ineffective drug prescriptions. They leverage individual molecular data to prescribe the appropriate treatment, saving money and improving lives. Their revolutionary blood-based molecular signature test enables providers and payers to make accurate treatment decisions, reducing unnecessary spending.

Built on more than a decade of experimental research, their platform truly represents the biology of disease. Scipher Medicine’s precision medicine approach identifies unique disease signatures, predicts drug responses, and discovers new drug targets. With a growing database, Scipher Medicine continues to refine its knowledge and influence the autoimmune disease market with tests like PrismRA, ensuring that every patient receives the appropriate treatment from day one. This company is revolutionizing drug prescribing and shaping the future of healthcare.


Ultimately, B2B2C businesses like the ones featured in this article involve a close partnership between two businesses to bring products and services to people. These companies embody the essence of B2B2C, connecting businesses and consumers in a way that improves experiences, streamlines processes and drives meaningful results.

This model has become popular because of the benefits it can bring to all businesses and consumers. This is why countless innovative startups are developing new solutions in new ways and entering new markets in the B2B2C field – all for a future where every challenge and problem will be solved by innovative solutions.

As technology continues to evolve, the impact of these pioneers is not only felt today. Nonetheless, it is a glimpse into the transformative potential that awaits us in the future of business and consumer interactions.

Featured Image Credit: Photo by Canva Studio; Pixel; THANKS!

Adam Torkildson

I am an investor in digital assets; founder of Tork Media; father, mentor and husband. I love being featured on new tech startups, especially in the AI ​​space.

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